Lee Jesse Gamble (June 28, 1910 – October 5, 1994) was an American professional baseball player. He was an outfielder over parts of four seasons (1935, 1938–40) with the Cincinnati Reds. For his career, he compiled a .266 batting average in 342 at-bats, with 21 runs batted in. He made only one error in 135 total chances in 77 games at the outfield for a .993 fielding percentage.
He was born in Renovo, Pennsylvania and later died in Punxsutawney, Pennsylvania at the age of 84.