Mandiana is a prefecture located in the Kankan Region of Guinea. The capital is Mandiana. The prefecture covers an area of 12,825 km.² and has a population of 335,999.
The prefecture is divided administratively into 12 sub-prefectures:
10°38′02″N 8°42′04″W / 10.63389°N 8.70111°W / 10.63389; -8.70111