Malotilate

Chemical compound

Malotilate (INN) is a drug that has been used in studies for the treatment of liver disease. It has been shown to facilitate liver regeneration in rats.^[1]

References

1. Niwano Y, Katoh M, Uchida M, Sugimoto T (1986). "Acceleration of Liver Regeneration by Malotilate in Partially Hepatectomized Rats". Japanese Journal of Pharmacology. 40 (3): 411–415. doi:10.1254/jjp.40.411. PMID 2423727.

• Bührer M, Le Cotonnec JY, Wermeille M, Bircher J (1986). "Treatment of liver disease with malotilate. A pharmacokinetic and pharmacodynamic phase II study in cirrhosis". Eur. J. Clin. Pharmacol. 30 (4): 407–16. doi:10.1007/BF00607952. PMID 3743616. S2CID 19898827.
• Siegers CP, Pauli V, Korb G, Younes M (August 1986). "Hepatoprotection by malotilate against carbon tetrachloride-alcohol-induced liver fibrosis". Agents Actions. 18 (5–6): 600–3. doi:10.1007/BF01964970. PMID 3766314. S2CID 3213262.
• Younes M, Siegers CP (May 1985). "Effect of malotilate on paracetamol-induced hepatotoxicity". Toxicol. Lett. 25 (2): 143–6. doi:10.1016/0378-4274(85)90074-8. PMID 4002245.