Salen refers to a tetradentateC2-symmetric ligand synthesized from salicylaldehyde (sal) and ethylenediamine (en). It may also refer to a class of compounds, which are structurally related to the classical salen ligand, primarily bis-Schiff bases. Salen ligands are notable for coordinating a wide range of different metals, which they can often stabilise in various oxidation states.[1] For this reason salen-type compounds are used as metal deactivators. Metal salen complexes also find use as catalysts.[2]
Synthesis and complexation
H2salen may be synthesized by the condensation of ethylenediamine and salicylaldehyde.[3]
Salcomine, a complex of salen with cobaltJacobsen's salen-Mn catalyst
Complexes of salen with metal cations can often be made in situ, i.e., without isolating the H2salen.[4][5]
^Cozzi, Pier Giorgio (2004). "Metal–Salen Schiff base complexes in catalysis: practical aspects". Chem. Soc. Rev. 33 (7): 410–421. doi:10.1039/B307853C. PMID 15354222.
^Shaw, Subrata; White, James D. (11 June 2019). "Asymmetric Catalysis Using Chiral Salen–Metal Complexes: Recent Advances". Chemical Reviews. 119 (16): 9381–9426. doi:10.1021/acs.chemrev.9b00074. PMID 31184109. S2CID 184486101.
^Tsumaki, T. (1938). "Nebenvalenzringverbindungen. IV. Über einige innerkomplexe Kobaltsalze der Oxyaldimine". Bulletin of the Chemical Society of Japan (in German). 13 (2): 252–260. doi:10.1246/bcsj.13.252.
^Diehl, Harvey; Hach, Clifford C. (1950). "Bis( N,N '-Disalicylalethylenediamine)-μ - Aquodicobalt(II)". Inorganic Syntheses. Vol. 3. pp. 196–201. doi:10.1002/9780470132340.ch53. ISBN 978-0-470-13234-0. {{cite book}}: |journal= ignored (help)
^Pier Giorgio Cozzi (2004). "Metal-Salen Schiff base complexes in catalysis: Practical aspects". Chem. Soc. Rev. 33 (7): 410–421. doi:10.1039/B307853C. PMID 15354222.