Derek Wilkinson (born July 29, 1974) is a Canadian former professional ice hockey goaltender.
Wilkinson played his entire National Hockey League career with the Tampa Bay Lightning. His NHL career started in 1995 and he lasted until the 1999 season. He appeared in 22 games in his NHL career.
He was the final head coach of the Charlotte Checkers of the ECHL, from 2004 until the team moved up to the American Hockey League in 2010.