Protein-coding gene in the species Homo sapiens
Exocyst complex component 6B is a protein that in humans is encoded by the EXOC6B gene.[5]
Function
In yeast and rat, Sec15 is part of a multiprotein complex that is required for targeted exocytosis.[5]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000144036 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033769 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b "Entrez Gene: Exocyst complex component 6B".
Further reading
- Brymora A, Valova VA, Larsen MR, Roufogalis BD, Robinson PJ (August 2001). "The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene". The Journal of Biological Chemistry. 276 (32): 29792–7. doi:10.1074/jbc.C100320200. PMID 11406615.
- Feng S, Knödler A, Ren J, Zhang J, Zhang X, Hong Y, Huang S, Peränen J, Guo W (May 2012). "A Rab8 guanine nucleotide exchange factor-effector interaction network regulates primary ciliogenesis". The Journal of Biological Chemistry. 287 (19): 15602–9. doi:10.1074/jbc.M111.333245. PMC 3346093. PMID 22433857.
- Wen J, Lopes F, Soares G, Farrell SA, Nelson C, Qiao Y, Martell S, Badukke C, Bessa C, Ylstra B, Lewis S, Isoherranen N, Maciel P, Rajcan-Separovic E (July 2013). "Phenotypic and functional consequences of haploinsufficiency of genes from exocyst and retinoic acid pathway due to a recurrent microdeletion of 2p13.2". Orphanet Journal of Rare Diseases. 8: 100. doi:10.1186/1750-1172-8-100. PMC 3710273. PMID 23837398.
- Borsani G, Piovani G, Zoppi N, Bertini V, Bini R, Notarangelo L, Barlati S (2008). "Cytogenetic and molecular characterization of a de-novo t(2p;7p) translocation involving TNS3 and EXOC6B genes in a boy with a complex syndromic phenotype". European Journal of Medical Genetics. 51 (4): 292–302. doi:10.1016/j.ejmg.2008.02.006. PMID 18424204.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
