Kuriyan did postdoctoral research work for one year supervised by Karplus at Harvard before becoming an assistant professor at the Rockefeller University. As of 2015[update] Kuriyan's laboratory studies the structure and mechanism of enzymes and other proteins that transduce cellular signals and perform DNA replication. The laboratory primarily uses x-ray crystallography to determine 3-D protein structures as well as biochemical, biophysical, and computational techniques to uncover the mechanisms used by these proteins.
^Journal of the National Cancer Institute: JNCI. U.S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health. May 1999. p. 830.
^"National Academy of Medicine Elects 85 New Members". National Academy of Medicine. 15 October 2018. Retrieved 2 May 2019.
^Kuriyan, John; Konforti, Boyana; Wemmer, David (2013). The molecules of life: physical and chemical principles. ISBN 978-0-8153-4188-8. OCLC 779577263.
^Kuriyan, John; Harvard University; Department of Chemistry and Chemical Biology (2006), Mechanisms of RAS activation at the membrane, OCLC 232369650
^Brünger, Axel T.; Kuriyan, John; Karplus, Martin (1987-01-23). "Crystallographic R Factor Refinement by Molecular Dynamics". Science. 235 (4787): 458–460. Bibcode:1987Sci...235..458B. doi:10.1126/science.235.4787.458. ISSN 0036-8075. PMID 17810339. S2CID 38261757.
^Schindler, T.; Bornmann, W.; Pellicena, P.; Miller, W. T.; Clarkson, B.; Kuriyan, J. (2000-09-15). "Structural mechanism for STI-571 inhibition of abelson tyrosine kinase". Science. 289 (5486): 1938–1942. Bibcode:2000Sci...289.1938S. doi:10.1126/science.289.5486.1938. ISSN 0036-8075. PMID 10988075.