The 2001 Tennessee Titans season was the Titans' 42nd season and their 32nd in the National Football League. The team won only seven games, and failed to qualify for the playoffs for the first time since 1998. After finishing 13–3 in the two prior seasons, defensive coordinator Gregg Williams was hired as the new head coach of the Buffalo Bills. Williams' departure contributed to the dropoff in wins, as the Titans went from second in scoring defense in 2000 to 25th in 2001. After the season, the Titans lost Bruce Matthews, who had been with the team since 1983 when they were the Houston Oilers, to retirement, ending a 19-year era for the team.
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