Sympathomimetic drug
Dioxethedrin (INNTooltip International Nonproprietary Name), or dioxethedrine, also known as 3,4-dihydroxy-N-ethylnorephedrine, is a sympathomimetic medication.[1][2][3] It was a component of the antitussive syrup Bexol (a combination of dioxethedrin, codeine, and promethazine).[4][5] It is an ephedrine derivative (and hence is a phenethylamine and amphetamine) and is described as a bronchodilator and β-adrenergic receptor agonist.[2][4] Analogues of dioxethedrin include dioxifedrine (α-methylepinephrine; 3,4-dihydroxyephedrine), corbadrine (levonordefrin; α-methylnorepinephrine), and α-methyldopamine.[1]
References
- ^ a b Elks J (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 444. ISBN 978-1-4757-2085-3. Retrieved 1 September 2024.
- ^ a b Milne GW (2018). Drugs: Synonyms and Properties. Routledge Revivals. Taylor & Francis. p. 494. ISBN 978-1-351-78990-5. Retrieved 1 September 2024.
- ^ Pschyrembel W, Dornblüth O, Zink C (2012). "Dioxethedrin". Pschyrembel klinisches Wörterbuch: Mit klinischen Syndromen und Nomina Anatomica (in German). De Gruyter. p. 358. ISBN 978-3-11-150689-0. Retrieved 1 September 2024.
- ^ a b "Dioxethedrin Hydrochloride". Inxight Drugs. Retrieved 1 September 2024.
- ^ Portmann M, Delage R (1964). "[The Antitussive Combination Dioxethedrine-Codeine-Promethazine]". Revue de Laryngologie - Otologie - Rhinologie (in French). 85: 1073–1081. PMID 14266725.
